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The Human Predictome

Human protein-protein interactions predicted with Alphafold-Multimer ( video tutoriali )

Predictions with SPOC >0.86 are 90% confident. For more details, click here.

WARNING: In silico screening has many limitations; all predictions require experimental validation.

Supported by NVIDIA through NAIRR.

Note that homodimers are excluded from results because they are often artifactually assigned high SPOC/AF-M scores.
Additionally, pairs may not have been run because they were either (not nominated by our classifier KIRC, or they were too large (>3,600 amino acids total)).

Pair Sets

Curated sets of pairs.